1, the hazards of kidney failure Because of the poor kidney function of the patient, the metabolic wastes in the body, such as urea nitrogen, creatinine and other harmful substances, there is no way to excrete through the kidneys to the body. These wastes can travel around with the blood, and if they enter the digestive tract, the gastrointestinal mucosa will be stimulated to cause nausea, diarrhea, vomiting and other symptoms, and the oral mucosa will be ulcerated, and the patient’s mouth will smell like urine. If the waste is discharged through the respiratory tract, it can cause urotoxic bronchitis, pleurisy, pneumonia, etc. The pericardium can cause urotoxic pericarditis when stimulated by urea. If the waste is excreted through the sweat glands of the skin, urotoxic cream can appear on the patient’s skin. Particularly serious is that the toxic substance infringes on the nervous system, which can make patients appear depressed, tired and weak, numbness of the limbs, dizziness and headache, etc. In heavy cases, drowsiness or restlessness, convulsions, coma, if not treated early can be life-threatening. 2, kidney failure patients should not be transfused kidney failure patients with anemia and other anemia is different, mainly due to the patient’s prolonged chronic renal insufficiency, the kidneys produce less erythropoietin, at the same time, the toxic substances retained in the body not only inhibit the production of red blood cells, and destroy the red blood cell membrane, accelerating the death of red blood cells. In addition, the presence of toxic substances such as erythropoiesis inhibitory factor in the blood makes it difficult for the already low erythropoietin to function. In addition, most patients have long-term anorexia and diarrhea, which can cause severe anemia due to the lack of iron, folic acid, protein and other nutrients in the body. Blood transfusion alone will not help in this type of anemia. If the patient’s transfusion is not fresh blood, but blood saved in the refrigerator, the decomposition of the dead red blood cells inside can aggravate the accumulation of nitrogen metabolites, adding to the burden on the already incapacitated kidneys. 3, kidney failure anemia how to do Although the kidney failure anemia patients should not be transfused, but the clinical can not be rigidly applied. Chronic kidney failure patients do not need blood transfusion when hemoglobin ≥ 6 grams, if hemoglobin < 6 grams, has caused serious hypoxia in various organs, the patient can be given a small amount of concentrated red blood cells or a small amount of multiple transfusions to improve cellular hypoxia. If the patient is found to have a significant bleeding tendency, platelet suspension or fresh blood needs to be transfused. If none of the above, erythropoietin, iron, folic acid and other drugs can be given in the treatment, while the patient's appetite can be regulated from the diet to supplement the missing nutrients. 4, the advantages and disadvantages of blood transfusion in renal failure chronic renal failure patients are often accompanied by anemia, and the ability to tolerate anemia is generally stronger than normal, many patients, although anemia is serious, but no obvious shortness of breath, chest tightness, pulse rate is not as fast as other anemic patients significantly. Blood transfusion can only temporarily improve anemia and relieve hypoxemia, but within a short period of time, red blood cells can fall to the original low level again. Excessive blood transfusion can cause an increase in blood urea nitrogen and potassium, which can aggravate the disease. It also increases the chance of importing hepatitis virus. Therefore, for patients with chronic renal failure combined with serious infection, acute hemorrhage, severe aluminum poisoning and the need for surgery, necessary blood transfusion is desirable, but fresh blood or a small amount of red blood cells should be transfused.