What to do about cough caused by lung adenocarcinoma is mainly based on the cause of cough. 1.If it is lung adenocarcinoma combined with lung infection or obstructive pneumonia, anti-infection treatment can be carried out, and the cough in the lung will be significantly reduced after anti-infection treatment. 2.If it is a large mass that blocks the bronchus and causes irritation and cough, radiotherapy of the mass can reduce the coughing symptoms, and chemotherapy can be done for lung adenocarcinoma at the same time. 3.If there is gene mutation, such as EGFR gene mutation or ALK gene mutation, you can use targeted therapy drugs, such as crizotinib, gefitinib, erlotinib or ositinib, which have obvious benefits to improve the symptoms of cough. Therefore, it is important to clarify what the cause of cough is when lung adenocarcinoma causes cough. Sometimes the cough is not necessarily caused by the tumor, but may be due to a bacterial infection, and anti-infection treatment will significantly reduce the cough.