Triple therapy is a clinical regimen used to treat Helicobacter pylori infection, and patients should not drink alcohol during the medication. Triple therapy refers to a proton pump inhibitor + two antibiotics, common medication regimens are omeprazole + clarithromycin + amoxicillin, omeprazole + amoxicillin + metronidazole and so on. Patients should not drink alcohol during the triple therapy, so as not to cause disulfiram-like reaction, which is easy to endanger life. Some patients drink alcohol during the medication is also easy to reduce the therapeutic effect of the drug, which should be taken seriously. Clinical mainly through the triple therapy treatment of H. pylori infection, so as to control the progress of the disease, relieve the disease caused by abdominal distension, belching, anorexia and other uncomfortable symptoms. In addition to triple therapy, some people with clear H. pylori infection can also use quadruple therapy. During the medication period, patients should pay attention to the rationality of the diet, avoiding the intake of cold, spicy and irritating food. It is recommended that patients use medication under the guidance of a physician, and should not use drugs or prescriptions on their own.