Before perfusion: The bladder should be emptied before perfusion, and make sure that no large amount of water, fluids and diuretics (e.g. hydrochlorothiazide and other drugs) have been taken within the last 2 hours.
During instillation: Keep your body relaxed during instillation so that the urethral muscles are relaxed to facilitate smooth entry of the catheter into the bladder.
Patients with conditions such as urethral stricture can explain to the outpatient physician in advance so that the appropriate size catheter can be changed.
After instillation: lie flat for 30-45 minutes after instillation, during which time the position is changed (supine, left lateral, right lateral, prone, in that order), which can be shortened if there is urinary frequency and urgency in patients with small bladders.
After urination, it is encouraged that more water should be consumed within 24h to expel residual drugs from the body, during which tea, coffee, alcohol, and cola-based beverages should be avoided to reduce bladder irritation.
Some adverse reactions may occur after intravesical chemical instillation therapy, mainly chemical cystitis and hematuria, which may manifest as urinary frequency, urinary urgency, microscopic or carnal hematuria, most of which can improve and disappear on their own after stopping instillation. Other rare adverse reactions include nausea, vomiting, fever, hair loss, and urinary tract infection. Therefore, it is encouraged to drink more water for 24 hours after the end of urination to excrete the residual drug from the body as soon as possible.
Special attention is paid to the fact that the first urine discharge after perfusion contains a large amount of chemical drugs, so it is recommended that the first urination be performed in a hospital.