In the middle of the night upset stomach may be caused by the following situations: 1, generally did not eat, or ate food to stimulate the stomach, you can eat hot food, drink some rice soup, do not eat cold and irritating food; 2, may be caused by gastrointestinal flatulence, the cause of the onset of the patient’s physique, overeating and stress related, you can massage the abdomen, drink more hot water, appropriate exercise to promote gastrointestinal excretion, or oral intestinal morbidities. 3, may be caused by gastric diseases, such as gastritis, peptic ulcer, gastric cancer, functional gastrointestinal disease, need to consult the hospital in a timely manner, to clarify the cause of the disease according to the primary pathogenesis of the treatment, given to the inhibition of acid gastric treatment. Usually diet should pay attention to light diet, do not eat cold stimulating food, do not eat too full dinner, less strong tea, coffee, quit smoking and limit alcohol.