There are more causes of muscle cramps, the common clinical factors are hypocalcemia, epilepsy, tetanus, rabies, high fever and other disease factors, but also can be seen in the muscle cold, fatigue and so on. 1. Hypocalcemia: when the patient’s body is deficient in calcium, causing hypocalcemia, the nerve excitability of muscle tissue increases, and the muscle will show symptoms of spasm and cramp. 2. Epilepsy: caused by abnormal discharges in the brain due to various reasons, and its seizures can cause cramps in the muscles of the limbs. 3. Tetanus and rabies: Cramps in tetanus and rabies are caused by the tetanus bacillus, rabies virus and the toxins it produces invading the nervous system. 4. Hyperthermia: patients with hyperthermia lose too much sodium due to profuse sweating, which leads to hyponatremia and cramps. 5. Muscle cold: muscle cold can lead to muscle spasm, but also lead to vasoconstriction, which in turn causes muscle ischemia, can also lead to muscle cramps. 6. Fatigue: muscle fatigue can lead to the accumulation of lactic acid in the muscle, which contains H ions that can stimulate the muscle, thus causing muscle cramps. It is recommended that patients seek timely medical treatment, improve the examination, clarify the cause of the disease, and be treated by a professional physician.