Timely repair of a skull defect is not only beneficial to the patient’s recovery, but it can also help to prevent the occurrence of some cranial syndromes. If the defect is not repaired for a long time, the brain will lose the protection of the skull, which will bring great damage to the brain tissues when the head is hit by external force or under the force. That is why it is important to repair cranial defects in a timely manner, no matter what the cause is in life. Although, cranial bone repair as a relatively routine neurosurgery surgery, the surgical risk is very low, will not cause any damage to the brain and the blood vessels supplying the brain, the vast majority of neurosurgeons, experienced doctors to complete this surgery is not a risk to the patient. However, after clinical research found that titanium mesh cranial repair, there are still some defects, common problems such as postoperative rejection, infection, chronic pain, material exposure, so it can not be used as the first choice of patients’ repair. In recent years, with the emergence and clinical use of polyether ether ketone peek material cranial bone repair plastic surgery, so that the majority of patients with cranial defects see a new hope. Currently, a number of minimally invasive surgeries have gained a reputation in the region for their remarkable results. In recent years, its Department of Neurosurgery has introduced the polyetheretherketone peek material cranial bone repair and plastic surgery from the hospitals in the medical association unit. This technology has four technical innovations compared with the cranial repair surgery carried out by other hospitals. On the basis of neurosurgical repair, further plastic surgery is done on the appearance, and the repair and plastic surgery are skillfully connected together, which can effectively avoid the problems of temporal muscle atrophy and asymmetry of the two sides after the surgery; in addition, the polyetheretherketone peek material cranial repair plastic surgery is to use the new artificial material peek as the implantation material, which is very close to the human body in all its properties. In addition, polyetheretherketone peek material cranioplasty is implanted with a new artificial material called peek, and the properties of peek are very close to those of the human skull, so there are basically no postoperative complications.