Treatment of non-gonococcal urethritis usually takes 7 to 14 days of azithromycin. Non-gonococcal urethritis is due to infection with mycoplasma and chlamydia resulting in urethral irritation, mainly through sexual intercourse transmission, both men and women can develop, manifested as men and women urinary frequency, urgency, urinary pain, urinary burning, urinary dribbling and so on. Male patients may also manifest as morning urethral discharge, female patients will be accompanied by increased vaginal discharge, yellowing, odor, vulvar itching, and severe pelvic infection may lead to tubal blockage infertility. Diagnosis can be confirmed by secretion examination, and oral azithromycin, clarithromycin, roxithromycin and other treatments need to be taken according to the drug sensitivity test. The course of oral azithromycin treatment is 7~14 days, and coitus is prohibited during treatment. Taking azithromycin may cause gastrointestinal adverse reactions, such as epigastric discomfort, nausea, vomiting, etc.; allergy to azithromycin is prohibited. Azithromycin needs to be taken under the guidance of a doctor, avoid self-medication to avoid adverse reactions.