Blood creatinine 139μmol/L is not serious if it is physiological creatinine elevation, but more serious if it is pathologic elevation. 1. Physiological creatinine elevation: the normal value of normal male blood creatinine is 53～106μmol/L for men and 44～97μmol/L for women, no matter male or female blood creatinine 139μmol/L is higher than normal. If you are young, rich in muscle content, more active, and your diet is based on meat and protein, it will cause physiological increase in blood creatinine, and there is no combination of organic diseases, so there is no need for special treatment, and it is not considered to be serious, and regular review can be done. 2. Pathological creatinine increase: the common cause of renal failure due to a variety of triggers, such as infection, fever, gastrointestinal bleeding, urinary tract obstruction, glomerulonephritis, etc., at this time the general condition is more serious, the need for specific causes of targeted treatment, if the treatment is not timely, the condition may be progressively aggravated. Clinical many patients will appear the phenomenon of elevated blood creatinine, it is recommended that patients timely regular hospital consultation, under the guidance of physicians standardized examination and treatment.