Cardiac glycosides include digitalis and others. They are mainly used in the treatment of diseases such as chronic heart failure and the control of ventricular rate in tachyarrhythmias such as atrial fibrillation and atrial flutter. However, attention should be paid to the existence of contraindications, the use of drugs need to be under the guidance of clinicians. There are many cardiac glycosides, and common clinical drugs include digitalis, digoxin, and mauve glycoside C. These drugs have the effect of enhancing myocardial contractility, lowering heart rate increasing ventricular filling volume increasing cardiac output, increasing renal perfusion pressure diuretic. These drugs are mainly used for acute and chronic congestive heart failure, atrial fibrillation, atrial flutter and other tachyarrhythmias ventricular rate control. However, attention should be paid to the fact that if nausea, vomiting, dizziness, irritability, etc. occur after the use of the drug, it is necessary to immediately stop using the drug and carry out resuscitation. For the existence of cardiac glycoside drug poisoning, ventricular tachycardia, ventricular fibrillation, hypertrophic cardiomyopathy, preexcitation syndrome with atrial fibrillation, are using calcium preparations, etc., at the same time, if there is hypokalemia, incomplete atrioventricular block, hypercalcemia, hypothyroidism and other conditions, need to be used with caution. Cardiac glycosides need to be used under the guidance of a clinician.