Traditionally, surgery on the upper abdomen is a contraindication to laparoscopic biliary surgery because the adhesions caused by upper abdominal surgery can prevent laparoscopic operation. However, many patients do develop bile duct stones again after upper abdominal surgeries such as major gastrectomy, radical resection of gastric cancer, cholecystectomy, bile duct excision and lithotripsy, resulting in high fever, jaundice, and even shock. Because of the gastrointestinal diversion of the gastrectomy and the huge bile duct stones, many patients cannot do minimally invasive duodenoscopic biliary sphincter excision and lithotripsy treatment (ERCP+EST), and therefore are forced to face another open surgery for bile duct stones. In my clinical practice for many years, I have successfully completed dozens of laparoscopic minimally invasive bile duct stone retrieval surgeries including major gastric resection, radical resection of gastric cancer, cholecystectomy, bile duct incision and stone extraction, and postoperative jugular cancer, including many cases of difficult laparoscopic bile duct stone retrieval surgeries after two and three operations on the upper abdomen, with a success rate of The success rate of the surgery was over 90%, which enabled these patients to avoid another major invasive open surgery. This procedure has brought minimally invasive treatment opportunities for the patients concerned and deserves to be further promoted to benefit more patients.