Good news for male patients: prostate cancer risk can be reduced through frequent ejaculation. The study’s findings were presented at the 2015 American Urological Association Annual Meeting. ”This vacuous recommendation is not a cliché and is now supported by strong evidence.” said Jennifer Rider, first author of the paper and an epidemiologist from the Harvard School of Public Health in Boston. “There are no modifiable risk factors for progression to prostate cancer, and the exciting thing is that this is a way to be able to change the risk.” Dr. Rider told Medscape Medical News. However, she also noted the existence of observable data and urged the need for extra caution in the presence of expressive factors. “The results are very surprising.” said Dr. Jesse Sammon from Henry Ford Hospital in Detroit, “It underscores the cancer epidemiology component of the study, which was pushed out to the Web.” “It’s hard to believe the high quality of the data.” So said Dr. Sammon after participating in the study. The data came from a professional follow-up of 32,000 men who have been followed for 18 years to date. During the study period, 3,839 men were diagnosed with incident prostate cancer, 383 of which were fatal. At the beginning of recruitment in 1992, all subjects were asked to report the monthly frequency of ejaculation during the earlier years at the 20- to 29-year-old stage and at the 40- to 49-year-old stage, which was entered into a computer by estimating the average number of times over a lifetime. After controlling for potential confounders, the risk of prostate cancer was reduced by 20% in men who ejaculated up to 21 times or more compared to men who ejaculated 4-7 times per month. This 20% reduction in risk was derived at ages 20-29 and 40-49 years with a mean survival (overall P trend < .0001). The majority of men aged 40-49 years (38.0%) reported 8-12 ejaculations per month; only 8.8% reported at least 21 ejaculations per month. dr. Rider suggested that "we should not be bound to the exact number of ejaculations, but rather focus on the quantitative response." She concludes, "Safe sex activity is good for prostate health." Notably, ejaculation frequency was not associated with the risk of high-level, progressive fatal disease, she reported. The exact reason for this is unknown. These results were updated as the follow-up study progressed. The original study was published 10 years ago in the American Journal of Medicine (JAMA. 2004;291:1578-1586). At the time, the researchers concluded that "high-frequency ejaculation may reduce the risk of prostate cancer overall and within organs." Medscape Medical News reported. A number of other studies have also reported an association between ejaculation frequency and prostate cancer risk, with risk protection with orgasm, Dr. Rider said, but these new data have three distinct advantages: first, the study is prospective and the data are long-term, whereas most other studies are retrospective; second, the study includes the largest cohort to date; and third, the study has specific information on ejaculation. specific information. The mean age of the subjects in this study was 59 years, the mean PSA score was 5 in 2008, most subjects were married, and men aged 40-49 years with at least 21 ejaculations per month were more likely to be divorced (11.8% vs. 4%-7%).