There are many reasons for the lack of hand strength, such as fatigue, anemia, electrolyte disorders, hypertension, cervical spondylosis, cerebrovascular disease, diabetes mellitus, hypothyroidism, colds and so on. 1. Exhaustion: Excessive exercise and fatigue can lead to weak hands, which can be relieved after rest and is not a symptom of disease. 2. Anemia: various types of anemia can cause insufficient blood perfusion to the tissues, which can lead to dizziness, fatigue, and can also be manifested as lack of strength in the hands. 3. Electrolyte disorders: Dehydration, hypokalemia, hyponatremia, and metabolic acidosis caused by excessive sweating or vomiting and diarrhea can also cause the symptom of lack of hand strength. 4. Hypertension: Hypertension can also cause dizziness, fatigue, and lack of hand strength. 5. Cervical spondylosis: cervical spine compression of local nerves and blood vessels may also cause dizziness, hand numbness, fatigue, etc., resulting in lack of hand strength. 6. Diabetes: Disorders of glucose metabolism can cause weakness in the limbs, which is manifested as lack of strength in the hands. 7. Hypothyroidism: Hypothyroidism may also lead to lack of strength in the hands, poor mental state and other manifestations. 8. Colds: viral infections caused by cold may cause weakness, resulting in lack of strength in the hands. There are many reasons for the lack of hand strength, there may be other reasons, you need to go to the hospital in a timely manner to check the cause of the disease.