The answer is yes, it can. Hepatitis B mothers should be seen throughout the entire process from preconception testing, medication during pregnancy, and postpartum newborn co-immunization. Why do some hepatitis B mothers take medication during pregnancy and is it safe? It is especially important to have regular liver function tests if you are positive for HBsAg, HBeAg and HBV-DNA. Chronic hepatitis during pregnancy is prone to develop into chronic heavy hepatitis, and pregnant women with cirrhosis of the liver are prone to ascites during pregnancy, which can also induce gastrointestinal bleeding; hypertension in pregnancy also tends to be more severe. Antiviral therapy with tebivudine, or lamivudine may be considered for pregnant women with recurrent abnormal liver function during pregnancy, where general liver-protective therapy is not effective, and high HBVDNA load. This needs to be done with informed consent and under the guidance of a specialist in person. If a previously delivered infant is HBsAg positive and has a high HBVDNA load during the current pregnancy, it is recommended that lamivudine or telbivudine be considered in late pregnancy to help prevent mother-to-child transmission.