1. There are several doses of vaccine: 5ug/dose for children and 10ug/dose for adults of hepatitis B vaccine produced in China. Within a certain dose range, the higher the dose of vaccine, the higher the positive rate of antibody conversion after immunization, and the higher the level of antibody in the blood, so that the protection period of human body is longer after the whole immunization. 2. Vaccination method and procedure: intramuscular injection, a total of 3 shots, according to the immunization procedures for 0, 1 and 6 months, for example: the first shot on January 1, the second shot on February 1 and the third shot on July 1. 3.Vaccination dose: newborn: 5ug/each time; children and adolescents less than 18 years old: 10ug/each time; adults: 20ug/each time; adults receiving dialysis or immunosuppressed patients: 40ug/each time. 4. How long can the vaccination last after successful vaccination: 5 to 10 years. Who cannot and need not be vaccinated with hepatitis B vaccine? Firstly, people with fever should not be vaccinated, and should be injected after the fever has gone down. Secondly, people with allergies, i.e. people who are allergic to many things, should be cautious and have epinephrine on hand when implementing immunization to prevent accidents. Hepatitis B virus carriers and hepatitis B patients also cannot induce an immune response with the hepatitis B vaccine. However, there is no harmful reaction to the vaccine in such people. People who are anti-HBs positive and have high levels do not need to be reimmunized because they already have protective antibodies in their bodies. However, if the antibody level is very low, which generally means less than 10 mIU/m1, a booster dose of hepatitis B vaccine is still needed.