A rise in ferritin from as much as 400ug/L to 700ug/L can be the result of diseases such as leukemia, liver cancer, and pancreatic cancer. These diseases can cause abnormal cell death or abnormal metabolism, resulting in the incorporation of ferritin into the serum, making ferritin values higher. 1. Leukemia: Diseases caused by a variety of factors, such as enhanced self-renewal of leukemia cells, uncontrolled proliferation, impaired differentiation, and impaired apoptosis, can lead to elevated ferritin. 2. Hepatocellular carcinoma: because hepatitis virus, cirrhosis, aflatoxin and other substances on liver cell damage and repair, oncogenes, proto-oncogenes and other substances can cause the impact of cancer, will lead to elevated ferritin. 3. Pancreatic cancer: When the growth of pancreatic cells is out of control due to long-term heavy smoking, heavy drinking, high-fat and high-protein diet, it may lead to pancreatic cancer, which will lead to elevated ferritin. The rise of ferritin from 400ug/L more to 700ug/L more may also be seen in chronic necrosis of the liver, chronic liver disease, cirrhosis and other diseases, if there is a rise of ferritin from 400ug/L more to 700ug/L more, you need to consult a doctor in time for treatment.