Creatinine 145 μmol/L is higher than normal. Creatinine is a toxin produced by muscle metabolism in the body, which is mainly metabolized and excreted by the kidneys. When the kidneys function abnormally, the excretory function is weakened, and the level of creatinine in the blood will increase. Normal creatinine is usually 53~106 μmol/L for men and 44~97 μmol/L for women, but the normal range of creatinine varies depending on the level of testing in each hospital. Elevated creatinine can be seen in excessive intake of meat food, exercise and other physiological reasons, usually after the elimination of these triggers, creatinine may return to normal; creatinine can also be seen in a variety of acute and chronic glomerulonephritis, urinary tract infections and other pathological factors. At this time, elevated creatinine usually represents a decline in kidney function. There may be other reasons for creatinine abnormality, it is recommended to go to the hospital for further clarification of the cause in order to avoid delaying the condition.