Important weapons for prostate cancer

  Twenty years ago, the incidence of prostate cancer in China was hovering at 1 per 100,000. However, various epidemiological data show that the incidence of prostate cancer has increased rapidly in the past decade or so. The incidence rate in Shanghai increased 3.5 times in 1997-1999 compared to 1985-1987, and reached 7.7/100,000 in 2000. The Beijing Health White Paper 2011 shows that the incidence of prostate cancer among men in Beijing rose from 5.53/100,000 in 2001 to 16.62/100,000 in 2010, an increase of 200.5% in 9 years, with an average annual increase of 9.2%.  At present, surgery, endocrine, radiotherapy and chemotherapy are the four basic methods of treating prostate cancer. 65-year-old Daddy Zhang used two of these methods for treatment, and as a result, early stage cancer developed into late stage cancer, so what happened?  The first thing you need to do is to get rid of the root cause of your prostate cancer. 65 year old father Zhang was diagnosed with prostate cancer four years ago, fortunately it was early. The doctor said it would be fine if it was cut, and after further consideration, he underwent testicular debridement surgery and has been taking androgen control drugs for the past few years after the surgery. But some time ago, he suddenly had inexplicable pain all over his body and went to the hospital for a checkup. It turned out that his prostate cancer had developed to an advanced stage and had bone metastases. He asked his doctor: Why is this happening?  Professor Long Zhixiong, vice chairman of the National Precision Radiotherapy Committee, introduced that he had encountered more than one case like Daddy Zhang’s. He lamented that surgery to cut the testicles is only a method of endocrine therapy, not a radical cure for prostate cancer, and that if Dad Zhang had undergone radiotherapy after surgery, the outcome might have changed.  The actual fact is that the prostate is an androgen-controlled organ that develops from cellular degeneration to cancer as a result of androgen-stimulated growth. Endocrine therapy also controls the production of androgens in the patient’s body, i.e. using drugs to bring androgens down to a minimum level. Surgery + endocrine therapy are the two most basic treatments for prostate cancer at present.  Professor Long further explained that surgery to remove the prostate or testicles is more effective for early stage prostate cancer, but it does not mean that the primary lesion can be completely removed and it is easy to recur; endocrine drugs used to a certain extent, 70% of people will develop drug resistance, which will also increase the risk of cancer recurrence after a long time. This is the root cause of the recurrence of Papa Zhang.  The target area determines the effect of radiotherapy The choice of radiotherapist is very important Radiotherapy, firstly, can be used as a post-operative adjuvant. Pre-operative prostate cancer specific markers (PSA) are high, or there are cancer cells remaining after surgery.  Secondly, radiotherapy can also be used as a means of radical treatment of prostate cancer. Radiotherapy can kill tumor cells rapidly by radiation and cut off the way of cancer cells spreading, especially for patients with early or locally advanced prostate cancer (stage A2-D1), because radiotherapy is less damaging and allows patients to live a high quality life. Some data show that its 15-year survival rate can reach 80%.  Where to have radiotherapy and who will give you radiotherapy is not usually given much thought by patients. However, it is closely related to the effectiveness of radiotherapy.  National Vice Chairman of Precision Radiotherapy, Prof. Zhixiong Long, said that each radiotherapy treatment looks like a repetitive process, but each time the patient will lie in a different position, and the doctor’s precise observation determines the accuracy of the irradiated target area. Some prostate cancer patients have heavy side effects or other reasons for fat loss, so the next time they lie in the same position, the target position may have 3-5 mm deviation, and the “target” will be distorted, and the radiotherapy effect will be reduced, and even radiation damage will occur.  The oncologist will determine whether the patient has cancer and the clinical stage, and determine the treatment means; the physiotherapist will make the radiotherapy plan according to the patient’s condition; and finally the radiotherapist will implement the plan, all three are indispensable. Prof. Long suggests that if conditions allow, it is better to have the same radiotherapist to carry out radiotherapy.