Treatment of brain metastasis from lung cancer

  Brain metastasis from lung cancer is a common and serious clinical condition and one of the common reasons for failure of lung cancer treatment. About 20% of patients with small cell lung cancer have brain metastases at the time of diagnosis, and the incidence of brain metastases in autopsy cases of small cell lung cancer patients is as high as 80%. Brain metastases occur in about 30% of non-small cell lung cancer patients during the course of their disease, with large cell undifferentiated carcinoma and adenocarcinoma being more common, followed by squamous carcinoma.  Vomiting is caused by the stimulation of the medulla oblongata respiratory center due to the increase of intracranial pressure, which leads to vomiting, mostly after headache, in the form of jet. The parietal lobe located in the middle of the cerebral hemisphere is specialized in sensation. Tumor in this area often causes unilateral limb pain and leg pain, which is also one of the symptoms caused by brain metastasis.  The fundamental treatment for multiple brain metastases from lung cancer is whole brain radiation with chemotherapy containing Vm26, but some scholars believe that the blood-brain barrier of patients with brain metastases is destroyed and all chemotherapy drugs can reach the brain, and now GP regimen is considered effective in treating brain metastases. The effectiveness of molecularly targeted drugs such as ERSA on brain metastases has also been reported. Single lesions or lesions less than 3 can be treated with gamma knife. To alleviate vomiting symptoms, daily water intake should be limited and diuretics such as dexamethasone or prednisolone and mannitol should be used. Chinese herbal treatments that have been shown to be potentially effective for brain metastases from lung cancer are eleuthero milk and opium biloba oil.