Bivalent E. coli with adsorbed vaccine, in the clinic usually refers to domestic bivalent HPV vaccine and imported bivalent HPV vaccine, both of which are used to prevent cervical cancer. There are differences in traits, specifications, expression systems, prices and other aspects. 1. Differences in traits: after shaking well, the domestic bivalent E. coli vaccine is a suspension; the adsorbed vaccine is mainly a turbid liquid. 2. Difference in specification: the specification of bivalent E. coli vaccine is 0.5 ml per vial; the specification of adsorbed vaccine is 0.5 ml per injection. 3. Different expression systems: E. coli has the advantages of low cost and high productivity; while the adsorbed vaccine is based on insect cells as the carrier, its productivity is relatively low. 4. Price difference: E. coli vaccine is about 350 dollars per injection; adsorbed vaccine is more expensive, about 600 dollars per injection. Vaccination must be carried out in accordance with the doctor’s instructions. After vaccination, you should pay attention to the observation, and if you have any physical discomfort, you should immediately seek medical treatment, which should be standardized under the guidance of the doctor.