Large cerebral infarction prevention, more commonly seen in clinical practice is through the treatment of underlying disease to achieve preventive effect. Specific preventive measures are as follows: 1, hypertensive patients, usually must keep blood pressure stable, if a blood pressure lowering drugs to lower blood pressure effect is not good, you can use two, two antihypertensive effect is not good, the use of three, or not down, we have to four joint use, so that different kinds of antihypertensive drugs superimposed on the role to stabilize blood pressure. After the blood pressure is stabilized, the internal environment can be slowly changed over several months or even years. In the state of blood pressure remains stable, you can start to reduce the drug, reduce to the end, or even take a kind of antihypertensive drugs, can keep blood pressure stable; 2, patients with diabetes must keep blood sugar stable, after the blood sugar is stable, the damage caused to blood vessels can also be reduced; 3, if there is wind heart disease, coronary heart disease and other causes of atrial fibrillation patients, should take long-term anticoagulant drugs warfarin, dabigatranate and other drugs, in order to prevent thrombosis If you have atrial fibrillation caused by wind heart disease or coronary heart disease, you should take long-term anticoagulant drugs such as warfarin and dabigatrans to prevent blood clots. If the plaque in the neck is large and thick, clinically more than 4mm thickness, aspirin and statin can be used together to take daily, which can stabilize the plaque and prevent the formation of thrombus.