Melasma is slow to treat and usually takes more than 3-6 months of treatment. For treatment, you can use topical hydroquinone cream or azelaic acid cream, and you can also try fruit acid resurfacing or salicylic acid resurfacing. For oral medication, you can take vitamin C, vitamin E and glutathione tablets orally, and tranexamic acid tablets, 25mg per day, which should be stopped during menstruation, and you can also try oral Chinese medicine. If there is no change of melasma in stable period within one year, you can do photorejuvenation treatment such as compound color light. Patients with melasma must protect themselves from the sun throughout the year by applying sunscreen in the morning and reapplying it once at noon if they go out in the afternoon.