Plantar warts are a disease caused by human papilloma virus infection, preferably on the heel, the front of the sole or between the toes at the pressure place, mainly in the form of yellowish or brownish-yellow patches. In the application of drugs, as far as possible to target the human papilloma virus and choose, common topical drugs are retinoic acid ointment, warts and warts ointment, acyclovir ointment, interferon gel, imiquimod cream, fluorouracil ointment, salicylic acid solution, zanax, etc., and the oral drugs are zinc sulfate, cimetidine and other immunomodulators. All of these drugs can be applied with relatively good results, and it is recommended to use the drugs under the guidance of a doctor and avoid self-medication. However, if the application of ointment is not effective, it is recommended to choose physical therapy, such as the application of cold nitrogen or microwave treatment.