For some patients with recurrent spontaneous abortions, doctors sometimes recommend lymphocyte immunotherapy, and many patients do not understand why it is necessary. Today, let’s learn more about it. 1.What is recurrent miscarriage (RSA)? Recurrent miscarriage refers to 2 or more consecutive spontaneous miscarriages with the same partner. It has a very complex etiology, including genetic, anatomical, endocrine, infectious and immunological factors. Studies suggest that 40-60% of recurrent miscarriages are related to immune factors. Half of the genes of the fetus originate from the father and should be rejected by the mother, but the majority of pregnant women do not experience rejection, which is related to the normal immune function of the mother. The presence of antibodies against the spouse’s lymphocytes in normal pregnant women prevents the maternal immune system from rejecting the embryo. In contrast, patients with recurrent miscarriage may lack certain antibodies, resulting in miscarriage when the embryo is treated as a foreign body by the mother and suffers from immune rejection. 2.What is lymphocyte immunotherapy? Lymphocyte immunotherapy is to extract a small amount of venous blood from the male partner, separate and extract lymphocytes, and inject them into the female partner’s inner anterior wall under the skin. A course of treatment is given every 20 days for 3 times. After six months of treatment, we try to conceive, and if we do not get pregnant within six months, we need to intensify the treatment once. After pregnancy, continue the lymphocyte immunotherapy, one course of treatment every 20 days, 3 times in total. 3.What are the preparations before treatment? Both spouses need to be checked for hepatitis series, HIV and syphilis. The male partner needs to have a vegetarian diet 3 days before the blood draw and cannot eat greasy and spicy food. If one of the couple is sick, they need to continue treatment after cure. 4.What are the precautions after treatment? The female partner should not eat greasy, spicy or seafood food within one week after receiving immunotherapy. If the injection site appears red, swollen, itchy, hard nodules is a normal reaction. If there is fever or allergy, you need to come to the hospital in time.