There is no TCM formula that can effectively treat bone metastasis of colon cancer. Bone metastasis of colon cancer has already belonged to the advanced stage of cancer, but it can be prolonged through targeted therapy, surgery, radiotherapy and other methods to improve the life cycle and quality of life of patients. Bone metastasis of colon cancer generally means that the cancer has reached the advanced stage, and there is no TCM prescription that can effectively treat advanced colon cancer for the time being. Advanced colon cancer is mainly treated by targeted drug therapy (cetuximab, bevacizumab) or palliative surgery. It can also be combined with radiation therapy and chemotherapy (e.g. 5-FU, mitomycin, etc.), which can prolong the life cycle of patients and improve the quality of life. Patients should maintain an optimistic and positive mindset in their life, and their family members should encourage them to establish confidence in overcoming the disease and actively cooperate with the treatment. Postoperative patients should have regular follow-ups to test their condition.