Cutaneous symptoms of filariasis: The adult worms migrate to the subcutaneous connective tissue and cause metabolic reactions due to their metabolites, resulting in the formation of rapidly developing localized carabid swellings, i.e., filarial masses (also called wandering masses), which can be accompanied by generalized fever, severe local pain, and itching of the skin. The masses are 5-10 cm in diameter, or hornet-sting type wandering edema, harder and more elastic than normal edema, sometimes red and swollen like dermatophagoides, which can occur at the primary site or spread to other sites, the masses last 2-3 days, mostly in the forearm, between the fingers, between the large fish muscle and thighs, gastrocnemius muscle, waist, etc., and can also appear in the groin and scrotum. Adult worms can crawl out of the body from under the skin, and can also invade various organs, such as the stomach and bladder. Occasionally, the worms invade the vocal fissure or urethra, causing severe symptoms. Most patients have no clinical symptoms other than an increase in blood eosinophils. The main clinical condition is recurrent skin swelling, called carabid swelling, which is caused by the metabolites of the adult worms migrating to the subcutaneous connective tissue and staying somewhere briefly to stimulate the local production of a non-severe inflammatory reaction. The painful lumps are itchy, mostly on the wrists and ankles, and are red in color, 2-3 cm in diameter, gradually expanding to 10-20 cm, lasting several days to weeks, and disappearing when the worms leave the lumps. Adult worms can also invade other organs, when invading the anterior chamber of the eye, they often migrate from under the conjunctiva, causing severe conjunctivitis. When the heart is invaded, it can cause pericarditis, myocarditis and endocarditis. In addition, it can also cause encephalopathy, peripheral neuritis and joint derivatives.