1, infection: under normal circumstances, the mucosal epithelial cells of the bladder lining secrete mucin, which has the role of adhesion to invading bacteria, and when urinating, the mucin with bacteria adhering to it is excreted with the urine. The residual urine is a good breeding ground for bacteria, and the bladder is not compensated and the mucosal defense function is damaged, so it is easy to cause urinary tract infection, which can be seen as frequent, urgent, painful urination, and even urge incontinence. It is very common for prostate enlargement to cause lower urinary tract obstruction, which leads to urinary tract infection. The poor urination, excessive residual urine, and increased pressure within the bladder can sometimes cause urine to reflux upwards from the ureter into the kidneys, and bacteria to reflux upwards, leading to pyelonephritis. In severe cases, uremia may occur. 3, bladder stones: in general, there will be cells and crystals in the urine constantly, because some stone forming substances in the urine, especially crystal components, such as calcium oxalate, calcium phosphate, calcium carbonate, ammonium magnesium phosphate, uric acid, etc., will inevitably occur in a supersaturated state, when drinking less water, sweating too much, etc., these components can not be fully dissolved in the urine, thus forming crystal precipitates appear in the urine, gradually The formation of microstones, constantly occurring this situation, the stones will continue to grow or increase. When obstructive diseases of the urinary tract such as prostatic hyperplasia occur, the microstones formed due to poor urination cannot be discharged smoothly with the urine and eventually form bladder stones because they accumulate more and more and get bigger. In addition, when prostate enlargement causes an increase in residual urine, it can easily cause urinary tract infections. When suffering from some bacterial infection that can break down the urea component of the urine, it can make the urine acidity rise. This urine environment can promote the formation of stones by precipitation of calcium phosphate, ammonium or magnesium salts. 4, other: some patients with prostate hyperplasia can have low libido, and a few can have hematosperm. The increase in abdominal pressure during long-term urination can cause the formation of hemorrhoids, prolapse and ventral hernia.