Chronic nephritis to renal failure for up to 20 years or more. Chronic nephritis is characterized by proteinuria, hematuria, and tubular urine as the basic features, with a history of more than 3 months, and may have edema and hypertension, and may also be combined with renal insufficiency. The disease is prolonged and progresses slowly, and eventually 50% of patients enter chronic renal failure and uremia. It is very important to perform renal puncture biopsy in patients with chronic nephritis. If the type of pathology is mild, blood pressure is well controlled, renal function damage is not obvious, and there are no complications, after reasonable treatment plus daily life maintenance, regular monitoring, as well as life as far as possible to avoid all kinds of drugs, food, other triggering factors that cause renal function damage, renal function progresses more slowly, and can last 20 years into renal failure.