The majority of chronic nephritis is accompanied by varying degrees of proteinuria, and it is beneficial to control or reduce proteinuria in chronic nephritis. First of all, in terms of diet, attention should be paid to the use of a high quality low protein diet, in general the daily intake of protein should be limited to about 30-40 g. It should be noted that high quality protein should preferably account for 60-70%, high quality protein mainly refers to protein from meat, milk, eggs, etc. It is important to remember that the daily protein intake should not exceed 1 g per kilogram of body weight. The second is not to do too much strenuous exercise, which may aggravate proteinuria. The third is that the appropriate protein-lowering treatment should be chosen according to the patient’s specific pathological type, kidney function, and other organ conditions, and the amount of proteinuria. The fourth is that AC EI and ARB drugs can be used in combination, and studies have shown that the combination of these two types of drugs can enhance the effect of reducing proteinuria. The fifth is that urine protein greater than or equal to 2.0g/24 hours, normal kidney function, or only mildly impaired, normal kidney size, renal pathological changes are not obvious or light, can consider the use of hormones and cytotoxic drugs, if the effect is not good, or other adverse reactions, should be gradually withdrawn to stop using.