In infantile thrush, in mild cases, white milk clot-like dots or small flakes can be seen covering the surface of the oral mucosa, which can fuse into a large area and cannot be easily removed. After forcible peeling, the local mucosa is flushed and rough, and there may be blood spillage, which has some effect on breastfeeding, and there may be no systemic symptoms. In severe cases, the entire oral cavity is covered with white film, which can even spread to the throat, esophagus, trachea and lungs, and can be accompanied by low fever, refusal to eat and difficulty in swallowing. Use 2% sodium bicarbonate solution to clean the oral cavity before and after breastfeeding, together with mycophenolate tablets for topical use, it has certain effect. Pay attention to the nipple cleaning and disinfection of breastfeeding equipment.