Thermoregulatory disorders are fevers resulting from abnormalities in the thermoregulatory center due to central nervous system pathology. Dysfunction of the central nervous system affects the function of the vegetative nerves and causes abnormalities in the function of the cardiovascular system, which may be related to physical, neurological, environmental, and genetic factors. Some patients are often in a state of depression and anxiety and are more likely to have thermoregulatory disorders. How to prevent thermoregulation disorders? Drugs act on the body’s temperature in different ways. The use of antipyretic agents can lower the body temperature when the thermoregulation point is raised by the action of endogenous or exogenous thermogenic sources. The use of antipyretics may interfere with the body’s resistance to infection, mask the condition, or cause adverse reactions to the drug. Drugs regulate body temperature in the following ways: alteration of the thermoregulatory mechanism, drug metabolic heat, hypersensitivity reactions, etc. Some drugs reduce body temperature by lowering the thermoregulatory point or heat dissipation. Drugs can prevent the appearance of signs and symptoms of fever by acting on the balance between the regulating point, neurotransmitters, etc. 1.Participate in more physical exercise and other physical activities to fundamentally improve physical fitness. 2.In order to protect the spleen and stomach, it is recommended not to consume spicy, fried and greasy food. 3, usually can eat more food to strengthen the spleen and nourish the qi. 4.Drugs act on the temperature of the body in different ways. Drugs regulate body temperature through the following ways: changing the regulatory mechanism of body temperature, drug metabolic heat, hypersensitivity reaction, etc. Drugs can prevent the appearance of signs and symptoms of fever by acting on the balance between the regulating points, neurotransmitters, etc. 5.When the effect of endogenous or exogenous pyrogenic source makes the regulating point rise, using antipyretic agent can lower the body temperature. Some drugs reduce body temperature by lowering the thermoregulation point or heat dissipation. The use of antipyretic agents may interfere with the body’s resistance to infection, mask the disease, or lead to adverse drug reactions.