About 1/3 of bile duct cancer patients have bile duct stones in combination, which shows that gallstones are one of the causative factors of bile duct (gallbladder) cancer, why are gallstones easy to induce bile duct cancer? It is because the recurring inflammation, stones and parasites in the gallbladder are likely to cause cancer in the bile cells due to the long-term frictional effect in the gallbladder. Why is it extremely difficult to detect bile duct cancer in early stage? Director Duan Dongming said that some patients mistake bile duct cancer combined with stones as a simple stone disease, and mistakenly take early symptoms such as poor appetite and upper abdominal pain as gastric disease for a long time, while once bile duct cancer is found in the middle and late stage, even if it can be treated surgically, the survival rate of patients is hardly more than 5 years. If recurrent gallstones cause recurrent bile duct infections, inflammation, jaundice and other symptoms, it may lead to bile duct cancer and should be operated as soon as possible. Some patients with gallstones have no symptoms such as pain, so they ignore the matter of gallstones. In fact, some cancers in the bile duct area are not painful and it is too late to go to the hospital when the whole body turns yellow (jaundice). If you experience persistent discomfort in the upper abdomen, developing jaundice, loss of appetite, weight loss, and generalized itching of the skin, you should be alerted. Some gallstones are not painful, which does not mean there is no problem. Stones that are not painful should also be checked regularly. Gallstones can be detected through routine physical examination, and ultrasound can be used to roughly screen for gallstones, which is not a difficult disease to diagnose and treat. However, some people find stones in the gallbladder, that is, they listen to the prescriptions for stone removal and stone crushing, which are not helpful to the disease. At present, medication for stone removal has been proven to be ineffective, and you should follow the guidance of a professional doctor after finding stones. Good eating habits, balanced diet structure and proper exercise can prevent gallstones, like exercise, which can lower the cholesterol level in bile. But for some people, must do more than so simple, the following groups of people must be checked regularly: 1, middle-aged and elderly people, especially obese fertile women, should have regular ultrasound examination, found to have gallbladder inflammation, gallstones or polyps, etc., more further examination and treatment. 2. Middle-aged and elderly people over 40 years old who suffer from gallstones and have a long history of recurrent attacks, accompanied by inflammation, jaundice and other symptoms, must undergo regular checkups at hospitals for early detection of the disease and whether it has a tendency to become cancerous.