The liver, located in the upper right abdomen, is the largest gland in the body and has the role of regulating the metabolic functions of the body and defending against diseases of the immune system. There are many factors affecting liver disease, which may be related to water pollution, long-term alcohol consumption, overexertion, improper diet, viral infections, side effects of drugs, and disorders of the autoimmune system. When liver disease occurs, there are usually precursory signs, mainly in the following areas: 1. digestive system symptoms: patients may have a series of digestive symptoms in the early stage, such as common loss of appetite, nausea, vomiting, abdominal distension and discomfort, which are related to liver disease causing liver decompensation and indirectly leading to digestive and absorption disorders; 2. liver discomfort: patients in the early stage of liver disease may feel pain or discomfort in the upper abdomen, when pressed or when over It is aggravated by exertion, mental tension, etc. Although rest can be relieved to a certain extent, the discomfort can be repeated several times; 3, bleeding: liver damage may cause the liver to reduce the synthesis of coagulation factors, increased capillary fragility, etc., causing the coagulation function is also damaged. Patients may have symptoms such as bleeding from the mouth and nose, gastrointestinal bleeding in the early stage. Especially women may have increased menstrual flow; 4. Skin symptoms: liver disease may show obvious changes in skin appearance, i.e. jaundice, yellow sclera of the skin. Patients may also have gradual darkening of skin color, dull and dark face, as well as dry, rough, swollen skin and other faces of liver disease. In addition, liver disease can also cause the inactivation of estrogen by the liver to diminish, leading to symptoms such as spider nevus and red palms. Due to individual differences, when patients experience liver disease precursors or physical discomfort, it is recommended that they should actively seek medical consultation and undergo targeted treatment according to the diagnosis. Paying attention to regular work and rest, nutritious diet and proper exercise in daily life will help patients recover.