History: The patient was a 71-year-old female with a 10-year history of hepatitis C. In February 2012, she had a sudden onset of right upper abdominal pain without any obvious cause and was rushed to a local hospital, where preliminary examination revealed liver lesions and abdominal fluid, so she was transferred to a tertiary hospital. The diagnosis was: primary hepatocellular carcinoma rupture and bleeding; post-hepatitis C cirrhosis. Emergency intervention was performed to stop the bleeding. A total of 3 hepatic artery chemoembolizations, 1 CT-guided radiofrequency ablation, and 1 hepatic artery infusion chemotherapy were performed, with good efficacy. The patient’s abdominal pain disappeared, mental and physical strength gradually improved, diet resumed as usual, and methemoglobin decreased from 2300ng/ml to 252ng/ml.