HBsAg positive, HBsAb negative, HBeAg negative, HBeAb negative, HBcAb positive is considered to be hepatitis B infection. Hepatitis B surface antigen is a relatively important indicator of hepatitis B. Hepatitis B surface antigen positivity indicates the presence of hepatitis B, while hepatitis B surface antigen negativity indicates the absence of hepatitis B. So HBsAg positive, HBsAb negative, HBeAg negative, HBeAb negative, HBcAb positive is considered to have hepatitis B. At present, it is hepatitis B I, V positive, may be the major triple and minor triple is in the transition between each other, it is recommended that need to further check the liver function, hepatitis B DNA and liver ultrasound to clarify the severity of hepatitis B, as well as the need for antiviral treatment. If the liver function is normal and there is no sign of cirrhosis, antiviral treatment may not be needed for the time being, but regular checkups are necessary.