The symptoms of multiple gallstones are clinically obvious and usually have the following manifestations: i. Patients will feel obvious biliary colic with paroxysmal spasms in the upper abdomen or right upper abdomen, and in severe cases, there will be further back pain. Second, patients will feel nausea, vomiting, bloating, indigestion and other uncomfortable gastrointestinal reactions, especially after eating some greasy food, this discomfort will be aggravated. Third, some patients may experience anorexia, constipation, jaundice, fever, etc. These are the obvious symptoms of multiple gallstones, but patients often confuse these symptoms with other diseases, thus missing the best time for treatment.