Radiofrequency ablation of hepatocellular carcinoma, as one of the radical therapeutic means for early stage hepatocellular carcinoma, has the same therapeutic effect as surgical resection and is gradually accepted by clinicians in various treatment departments. As a minimally invasive treatment, it has been widely carried out in hospitals at all levels. However, there are undoubtedly cases of over-indication and even over-indication of treatment, and the consequent risk of complications cannot be ignored, in addition to the waste of medical resources. The above achievements are mainly based on the following points: (1) Adequate preoperative discussion. The ablation team fully communicates with the patient before each treatment case to gain trust. In addition to reading the preoperative imaging data in person, the chief radiologist will be consulted in each case to ensure an accurate assessment of each patient. (2) Perfect preoperative planning. Using advanced image fusion-navigation, ultrasonography and other means, we have a precise preoperative plan for each case, such as anesthesia, patient position, applicable needle type, number of puncture needles, selection of puncture path, image guidance method, expected ablation range, immediate assessment means, etc., to ensure that no error occurs in each step. (3) Fine operation. For each case, we design fine operation steps and strive for complete ablation at one time; we do not blindly pursue speed. (4) Perfect multidisciplinary cooperation. We have established close contact with hepatobiliary surgery, interventional radiology, etc. We have a common consultation system, select the best treatment plan for patients, fully understand the advantages of each discipline, and do not pursue a single one, but truly achieve comprehensive treatment. (5) Practical follow-up system. We establish a file for each patient and follow up regularly. The continuity of treatment is maintained.