Nodular acne, a more focused type of acne, is clinically manifested by the appearance of nodules of varying sizes on the cheeks and other areas, which can be painful to touch. Treatment is as follows: 1. Oral medications: such as isotretinoin pills, vincristine capsules and other drugs to improve keratinization. 2. Oral anti-inflammatory drugs: such as azithromycin. For some conditions, good economic conditions can be combined with photodynamic treatment; for severe nodular acne, the effect is also very good, often after 2-3 times of treatment will have a significant effect. 3, the use of red and blue light irradiation: Chinese medicine hard cream of the inversion, Chinese medicine soup oral, etc., often also has a good effect.