Topical creams for acne are not hormones because acne is an inflammation of the hair follicles and hormone use will make the inflammation worse. If you have acne on your face but feel that it is an allergy to use creams like dermatoprene, which can quickly make facial papules and pustules increase in size, the mistake is that one is that hormone creams cannot be used for the treatment of inflammation of the hair follicles, and the second is that strong hormones are not recommended for use on the face. Western topical medications for the treatment of acne are mainly of the following two types: 1. Topical acne-solubilizing drugs: Currently, the main drugs used are retinoids, which can be used topically to reduce the hyperkeratosis of the epithelial cells of the hair follicles and the stickiness of the stratum corneum, thereby reducing the formation of microcomedones and accelerating their discharge. 2, topical anti-microbial drugs: Benzoyl peroxide is a strong oxidant and anti-microbial drug, which can slowly release neo-ecological oxygen and benzoic acid after topical application, which can effectively reduce Propionibacterium acnes and Staphylococcus epidermidis in acne lesions, and also reduce free fatty acids in skin surface lipids and reduce oxygen free radicals, thus playing a therapeutic role. In addition, some topical antibiotic creams can directly sterilize and anti-inflammatory to play a therapeutic role.