Acne is a common adolescent skin disorder and is referred to as “acne” in Chinese medicine. The disease is characterized by polymorphic lesions such as pimples, papules, pustules, and nodules. Acne occurs on the face and upper chest and back, especially on the face, and is easily recurring, and most patients do not recover. It seriously affects the appearance, which in turn damages the self-confidence of patients. Clinical practice has shown that the combination of Chinese and Western medicine is more effective in treating acne and has fewer side effects. Therefore, taking Chinese herbal granules is a good choice in the treatment of acne. Chinese herbal medicine decoction-free granules are not only easy to use and convenient for patients to take, but also avoid the adverse effects on the efficacy of the decoction process due to improper operation. Modern understanding of the etiology and pathogenesis of acne 1. Wind-heat external attack is the primary cause of acne, but it can also be the cause of recurrence. Wind-heat is a Yang evil, and its nature is good at inflaming the upper part of the body, so wind-heat mostly invades the upper part of the body. The heat burns the blood channels and blocks the pores, resulting in localized skin congestion and acne. 2, lung and stomach damp heat facial skin mainly by the lung and stomach meridian division. “The lung is also the skin, and its glory is also the hair”. In the five elements theory of Chinese medicine, lung is gold and kidney is water. If there is a deficiency of kidney yin in the body, kidney water cannot be nourished on the lung, which leads to a deficiency of lung yin. At the same time, the lungs and the intestines are in close proximity to each other, so if you do not eat well, you may stagnate dampness in the large intestine, which will lead to heat in the lungs and stomach, leading to acne, pimples and pustules. 3, phlegm and blood stasis are intertwined in acne for a long time, consuming Qi and hurting Yin. The phlegm and blood stasis are intertwined, preventing the flow of qi and the smooth flow of meridians, and blocking the local area, forming nodules, cysts, scarring, and accumulation. 4.Dysregulation of the Qi and Qi is not regulated, the blood is not filled. The blood that should be left is not yet gone, blood stasis. Both of them can produce blood heat over time. Blood heat may consume yin and fluid over time, and yin deficiency leads to blood deficiency, or burn the veins and collaterals, resulting in blood stasis from the menstruation. The cycle repeats, when the menstruation can not be under the time, is when the condition is aggravated, so the patient at this time the symptoms of the lesions than usual increased or aggravated. 5, kidney yin deficiency kidney for the innate essence, the master of growth and development and reproduction. The kidneys produce the heavenly sacrifice is the substance that directly affects human growth and development and reproductive function. If the kidney yin is not enough, the women’s two seven and men’s two eight phase fire lost the restraint, resulting in the heavenly sacrifice too vigorous, through the meridian on the steam head. At the same time, insufficient kidney yin cannot nourish the yin of the lungs and stomach, and yin deficiency and internal heat are the main causes of acne. The pathogenesis of acne is not caused by any single factor. Since its pathogenesis is more complex and relates to endocrine, immune, follicular microorganisms, sebaceous gland keratinization, etc., it should be considered from multiple aspects during treatment and prevention. Western medicine has become the commonly used drug due to the advantages of easy to use, fast effect, clear composition and relatively perfect dosage form, but western medicine is easy to repeat. Chinese medicine is a comprehensive treatment, which has good long-term effect and is not easy to recur after healing. Therefore, the combination of Chinese and Western medicine is the best choice for the treatment of acne, because it is effective and can prevent recurrence.