Chemotherapy regimens for adjuvant chemotherapy or concurrent chemoradiotherapy for stage IVA and IVB undifferentiated thyroid cancer

by Specialist

Protocol

Dosage

Frequency

Paclitaxel/carboplatin

Paclitaxel 50 mg/m2, carboplatin AUC 2 mg/m2 IV

Weekly

Docetaxel/Doxorubicin

Docetaxel 60 mg/m2 IV , Doxorubicin 60
mg/m2 IV (subject to polyethylene glycolated fexofenestrin support)

every 3-4 weeks

Docetaxel/Doxorubicin

Docetaxel 20 mg/m2 IV , doxorubicin 20
mg/m2 IV

Weekly

Paclitaxel

30 to 60 mg/m2 IV

weekly

Cisplatin

25 mg/m2 IV

Weekly

Doxorubicin

60mg/m2 IV

every 3 weeks

Doxorubicin

20 mg/m2 IV

Weekly

Note: AUC, area under the concentration-time curve; IV, intravenous drip