The fact that 70% of patients with diarrhea do not require antibiotics (except for stools containing pus and blood or routine stool tests that reveal leukocytes 2+ to 3+) does not mean that they do not need medication, some of which are highly effective for patients with diarrhea. One class of drugs is intestinal mucosal protectors, commonly known as Simethicone (also known as Bicillin and Montelukast). After oral administration, these drugs are widely covered on the surface of intestinal mucosa, fixing and adsorbing harmful pathogens and toxins, making it difficult for pathogens to invade the intestinal wall, protecting and promoting the regeneration and repair of intestinal mucosa. Another class of drugs is micro-ecological regulators, common ones are Pepcidone, Meconium, Mammazine, Pauleon, etc. There are many normal bacteria in the human body, such as bifidobacteria and fecal cocci, which are mainly distributed in the intestine and are indispensable for human life activities. If the number of normal bacteria decreases or the ratio is out of balance, the growth of harmful bacteria will increase and diarrhea will further aggravate the imbalance of flora. Microecological preparations are normal bacteria in the intestine mainly Bifidobacterium and Lactobacillus, etc., which can be supplemented to restore the number of normal flora and serve the purpose of treating diarrhea after oral administration. At present, zinc supplementation and microecological therapy are becoming another important aspect in addition to fluid supplementation in the prevention and treatment strategy of infant diarrhea. The World Health Organization (WHO) has recommended globally 10-20 mg of zinc orally daily for 10-14 days for children under 5 years of age with acute or chronic diarrhea. Zinc is an essential component of more than 200 metalloenzymes in the body, plays an important role in the development and regulation and maintenance of the immune system, and also improves the body’s ability to resist damage. Zinc plays an important role in pediatric intestinal structure and function. Zinc deficiency can lead to intestinal villi atrophy and decreased intestinal disaccharidase activity, and zinc supplementation can accelerate intestinal mucosal regeneration and increase brush border enzyme levels. Home treatment guidance is most important to prevent dehydration in patients with mild cases. There are 3 ways to prevent dehydration: ① Rice broth with salt, 500 mL of rice broth with 1.75 g of salt (i.e. half the cap of a beer bottle). ＜Drink 1 bottle per day for those <2 years old, 2 to 4 bottles per day for those >2 years old, and 4 to 8 bottles per day for adults. How much is appropriate to drink, mainly depending on the amount of urine and the usual normal as much as possible. ②Salt and sugar water, 500 mL of plain water, add 10 g of sugar or glucose, then 1.75 g of fine salt. ③Take Oral Rehydration Salt III (ORS), available at all major pharmacies, and take it with water as prescribed. When you have diarrhea, you still need to insist on eating. You must continue to eat when you have diarrhea, and you cannot rely on infusions, tonic drugs and nutrients to replace eating. So, what kind of meals should be eaten during diarrhea in order not to aggravate diarrhea but also to prevent malnutrition? In principle, the diet is required to be easily digestible, nutritious, high in calories, high in protein, and not too much oil and lactose, but not an oil-free or lactose-free diet either. The concentration of white sugar should not be too high, a little sweetness is enough. General fruit (except bananas and other easy to slip intestines) can also be eaten, but fresh and clean, do not eat frozen. Now some hospitals in China have developed dairy products suitable for children with diarrhea to take, with comprehensive nutrients and better results in preventing diarrhea and malnutrition. For patients treated at home, they can eat thin rice and egg noodles. If available, add broth, chopped beef and chicken, cook for 1 to 2 h on a gentle fire, remove the dregs and cool, then skim off the upper layer of oil. If necessary, drink fresh fruit juices such as watermelon juice. Tip: What kind of situation should be treated immediately in hospital Patients who are not well after 3 d of treatment and show one of the following manifestations should be treated immediately in hospital: ① increased stool; ② inability to eat; ③ frequent vomiting; ④ obvious thirst; ⑤ fever; ⑥ blood in stool. If the mouth is very dry, little urine, hoarse voice, no tears and no sound when crying, and poor skin elasticity, it means that the patient has progressed to severe dehydration, and the family is advised to send the patient to the hospital immediately.