Erythema labialis round or oval is a chronic connective tissue disease of the skin-mucosa with lesions mainly confined to the skin and oral mucosa. The mucosal lesions of DLE appear as oval or circular lamellar erosions with well-defined borders, and the lesion area is concave and disk-like, surrounded by shorter white streaks arranged in a radial pattern. The red mucosa of the lower lip is the preferred site of DLE. It starts as a dark red papule or plaque, and then forms an erythematous lesion with a lamellar erosion, about 0.5 cm in diameter, with a concave disc-like center, surrounded by a red halo or visible dilated capillaries, and short white streaks arranged in a radial pattern at the periphery of the halo. Self-examination: The mucosal lesions are usually red on the lower lip, with round or oval erythema, slightly concave in the center, slightly elevated with dark red edges, and surrounded by a white radiolucent pattern. The lip lesions often go beyond the red lip edges and involve the skin, with blurred skin boundaries. There is hyperpigmentation or hypopigmentation around the lesion area. The skin lesions are usually found on the head and face and are characterized by scaling, dilated capillaries, follicular keratin plugs, hyperpigmentation and/or hypopigmentation, and scar formation. The typical manifestation is “butterfly spots” around the nose.