Erythema labialis round or oval is a chronic connective tissue disease of the skin-mucosa, with lesions mainly confined to the skin and oral mucosa. It starts as a dark red papule or plaque, then forms an erythematous lesion with a lamellar erosion, about 0.5 cm in diameter, with a concave disk-shaped center, surrounded by a red halo or visible dilated capillaries, and short white streaks arranged in a radial pattern at the periphery of the halo. This chronic tissue disease is more difficult to detect, but daily protection work done well can still largely avoid or alleviate the onset of the disease. Daily protection: 1, establish optimism, treat the disease correctly, build confidence to overcome the disease, regularize life, pay attention to the combination of work and rest, proper rest, prevent infection. Avoid drinking alcohol and excessive fatigue. 2.Remove all kinds of causative factors, including all kinds of possible internal drugs, chronic infection lesions, etc. Avoid irritating external drugs and all external stimulating factors. 3, avoid sun exposure and ultraviolet radiation, especially in the active period, when necessary, can add anti-sun medication such as 3% quinine ointment, compound titanium dioxide ointment, 15% para-aminobenzoic acid ointment, etc. Other, such as cold, X-rays and other excessive exposure can also cause the exacerbation of the disease, should not be ignored. 4, to hydrazinophthalazine, procaine, penicillamine, antibiotics and sulfonamides to be reasonable role. 5, patients should be birth control, active period need to avoid pregnancy, if there is renal impairment or multi-system damage, it is appropriate to strive for early therapeutic abortion.