Erythema labialis round or oval is a chronic connective tissue disease of the skin-mucosa with lesions mainly confined to the skin and oral mucosa. The mucosal lesions of DLE appear as oval or circular lamellar erosions with well-defined borders, and the lesion area is concave and disk-like, surrounded by shorter white streaks arranged in a radial pattern. The red mucosa of the lower lip is the preferred site of DLE. It starts as a dark red papule or plaque, then forms an erythematous lesion with a flaky erosion, about 0.5 cm in diameter, with a concave disc-like center, surrounded by a red halo or visible dilated capillaries, and short white streaks arranged in a radial pattern at the periphery of the red halo. Common complications of the disease Squamous cell carcinoma of the skin:Squamous cell carcinoma, also known as dermatoid carcinoma, mainly starts from the skin covered with squamous epithelium. The lid margin at the junction of the skin and conjunctiva is the most frequent site. These carcinomas are more malignant than basal cell carcinomas. They develop more rapidly and are more destructive. It can destroy the eye tissue, invade the paranasal sinuses or the skull, and metastasize to the preauricular or submandibular lymph nodes through lymphatic vessels, or even cause systemic metastasis.