Can gammaglobulin treat chronic fatigue syndrome?

In today’s fast-paced, high-stress life and work environment, the number of patients with chronic fatigue as the main complaint is increasing, and chronic fatigue syndrome has become a health problem that cannot be ignored and has become a hot issue of concern for researchers at home and abroad.

In April 1987, the Centers for Disease Control and Prevention (CDC) officially named chronic fatigue syndrome as a group of syndromes characterized by chronic and persistent or recurrent mental and physical fatigue.

Chronic fatigue syndrome diagnostic criteria: 1, fatigue causes severe loss of behavior for more than 6 months; 2, must be accompanied by at least four of the following symptoms: memory loss, impaired concentration of thought, loss of restorative sleep, myalgia or muscle stiffness, polyarticular pain, headache, sore throat, swollen lymph nodes, excessive fatigue after activity; 3, must exclude other diseases that clearly cause chronic fatigue.

The etiology and pathogenesis of chronic fatigue syndrome are unknown and may be related to viral infections, overexertion, psychological overload, and other factors. These factors can lead to abnormal immune system function, neuroendocrine system dysfunction and other symptoms.

Measures used: 1. Behavioral therapy: Establish a healthy lifestyle, regular living, comprehensive and balanced nutrition, moderate exercise, quit smoking and limit alcohol, maintain psychological balance, etc. Modern medicine proves that continuous psychological tension and psychological conflict will cause mental fatigue, free function decline, prone to various diseases.

2, medication: anti-anxiety, antidepressant drugs, hypnotic drugs, vitamin drugs, etc.

Now some people think that supplementation of gammaglobulin can strengthen the body, relieve fatigue and treat chronic fatigue syndrome. Is there any truth in this?

Let’s first understand the components and effects of gammaglobulin. The clinically used gammaglobulin is divided into two types according to its source: one is human gammaglobulin from healthy human venous blood; the other is gammaglobulin from healthy maternal placental blood. It contains various antibodies that healthy human serum has and can be used for the prevention and treatment of immunodeficiency diseases as well as many viral and bacterial infections.

However, the immunity produced by gammaglobulin injected into the body is passively given, not actively produced by itself, and is usually excreted in 2 weeks, after which the level of gammaglobulin in the body returns to its original level. Moreover, the human body can synthesize gammaglobulin itself, so if foreign drugs are used frequently, it will inhibit the production of its own antibodies, thus reducing the body’s ability to fight diseases. As gammaglobulin is a blood product, in case the source is not strictly controlled, it can cause blood contamination and infect healthy human beings with diseases, and after all, foreign gammaglobulin is a “foreign substance” to the human body, which may cause allergic reactions after injection.

In short, gammaglobulin is not a panacea, use it to prevent disease, enhance physical fitness, lack of adequate scientific basis.