Encephalitis can be treated aggressively to reduce fever. Encephalitis can be seen as viral, bacterial, tuberculosis, fungal, and autoimmune encephalitis. The intracranial infection leads to headache, fever, neurological deficits and, in severe cases, seizures. The cause of encephalitis should be identified and the patient should be given anti-inflammatory, antiviral, anti-tuberculosis and antifungal treatment. Most of the patients with encephalitis can get significant relief after active treatment, so the patient can reduce the fever and some of the symptoms of neurological deficits can be significantly improved after treatment. For patients with encephalitis, if the patient’s condition is severe, dehydration and cranial pressure-lowering drugs should be applied when necessary to relieve the compression symptoms caused by increased intracranial pressure.