Inner monologue of pulmonary ground glass shadow

  I have a very interesting name in Chinese, “pulmonary frosted glass shadow” or “GGO” in English, and I was found on a computer tomography (CT) scan of the chest as a cloudy, faint shadow of mildly increased density that looks like frosted glass, hence the name GGO. I can grow diffusely (Figure A) or only locally, looking like a small frosted glass nodule (Figure B).  Don’t talk about me, I’m not necessarily a bad person (cancer, ca, cancer). Sometimes, lung inflammation (Figure C), bleeding (Figure D), and fibrillation (scarring after inflammation) (Figure E) can make me a bad person, but more often than not, I am still a bad person. I grew up with an ideal: I want to fight for control of my body, I want to be the boss!  I must have grown gradually from small to big oh, not at the beginning to become a giant (Figure f). When I was a child (<1 cm), I was pure, low density, round-faced and well-defined, I was not necessarily a bad guy at that time, you call me pure GGO (Figure B), and after excision it was mostly confirmed as adenomatous atypical hyperplasia (AAH, precancerous lesion) (Figure G), or adenocarcinoma in situ (TIS, no invasion of the surrounding vascular interstitium, no metastasis) (Figure H), or even in extreme cases it could be microinvasive adenocarcinoma in situ (MIS, invasion of <5 mm into the surrounding vascular interstitium, potential risk of metastasis) (Figure I).  When I grow progressively worse, it may cause an increase of solid component and become less pure, you call me mixed GGO (Figure J); sometimes, I also have lobulated, burr (Figure F), vacuolated (Figure K), pleural depression (Figure L), dense vascularity and other changes, by which time I am mostly already a bad guy, you call me invasive adenocarcinoma, malignant tumor. The cellular children in my body like to enter the human blood vessels, swim in the red sea, choose any site to set up camp, you call this metastasis, but only in this way, I am the boss to be called a real name, there are people under me, is not it?  Speaking of which, is not a little afraid of me? Oh, at first I was also very weak, not able to break through the intercellular connection, and can not enter the blood vessels. Only give me sufficient time, I will become stronger, gradually break through the layers of barriers to achieve transfer, which takes two or three years or more, related to the immunity of the body. When I am discovered by you, there is no need to panic: when I am small and pure, you can follow up and observe, generally speaking <8 mm can be followed up once in 3-6 months ct; if it is already >8 mm, or there is a tendency to grow up on follow-up, or there are many signs of bad guys, then deal with me early, otherwise my cellular subjects will sooner or later occupy important parts of the body, after which I am the real boss; if If I don’t change in two or three years of follow-up, then basically there is no problem, but not absolutely. When the immunity of the body is strong, I grow very slowly, even in a static state, but at the right time I will also explode, unless I was originally caused by lung inflammation, bleeding, which will shrink or even disappear, while the fibrosis created by me will not change.  When it comes to dealing with me, I can’t help but feel palpitations, I was born from the same root, but we share the same body. You most often use a minimally invasive thoracoscopic lung surgery (video-assisted thoracic surgery, VATS) to brutally remove me. Although sometimes I am too small and well hidden to be easily found by you, you humans have invented many more methods of GO localization, such as Hook-wire, coil, and intraoperative ultrasound ……. Recently, there are people who use Stereotactic Radiotherapy (SRT) to deal with me, using radiation focus to burn me to death and bake me, which is claimed to be better than VATS surgery, but there are still controversies. About this I report two points: first, surgery to remove me, then I really do not exist, SRT is only after a period of time may make me die, but may be one of my cellular people is very strong, self-limiting to protect the core and survived, oh, of course, in the future may also be malnutrition and starvation, but who knows? What if I am very hungry? Secondly, surgery also has risks, for the elderly, weak, sickly people may have a lot of complications, people who really can not stand surgery can choose SRT, or you hang I also have to accompany the funeral.  All in all, my name is GGO, more often than not, I still act as the bad guy. I like hazy days, tiny particles, people who stay up all night, smoke and drink, lack of exercise and have low immunity, with you, I can be born in this world. Give me more time to grow, oh, I will be able to soar in your body, blossom everywhere, I desperately want to become stronger, become the master of the world inside, it all comes from my very young, very pure when I have a big ideal: I want to be the boss!