Infertility is a common disease among women, and although the end is simply the inability to bear children, its etiology is quite complex, and may have both organic lesions and functional disorders, as well as psychological causes. In a considerable number of patients, what is emphasized is organic lesions, what is belittled is functional disorders, and what is ignored is psychological disorders. In fact, psychological disorders can also lead to infertility, and they are also diseases that require careful treatment. It is especially important to emphasize that psychological disorders are more painful, more troublesome and more in need of early treatment for patients. It is often said that heart disease is the most painful. Although this statement is biased, but to some extent is not without truth. Nowadays, a family of three is the basic “pattern” of the majority of families, and once the goal of having a single child cannot be realized, it is indeed a “trauma” for a family. The severity of this “trauma” varies from person to person. In order to explore the underlying causes of psychological disorders of female infertility and to find more accurate and targeted treatment measures, medical doctors have conducted a lot of clinical research. According to relevant reports, it is confirmed that the psychological disorder of female infertility is related to her age, occupation, age of marriage, years of infertility, attitude towards infertility, sexual life satisfaction and cultural level. The psychological barriers of female infertility patients are mainly reflected in the sense of low self-esteem, uneasiness, nervousness, reduced socialization, lack of interest in life, irritability, unwillingness or taboo to talk about fertility with others, which is especially prominent among infertility patients with low literacy level in rural areas. Of course, this is related to the fact that rural areas are deeply influenced by traditional ideas and concepts, and they think more about their future lives and worry about losing their livelihood security in the future. Secondly, it is also related to the existence of “weak links” in their own coping ability, ideology and self-regulation. Women’s long-term infertility, especially after multiple treatments have no effect, often lead to interpersonal sensitivity, anxiety, depression, paranoia, with the prolongation of marriage, age, psychological pressure is even heavier, and some even there is a sense of loss of “no one else”, the mental pressure is further aggravated, and more and more lack of confidence in the cure. It should be noted that the psychological condition of female infertility has a very close relationship with mental capacity and personality. The psychological pressure is especially obvious in patients with high nervousness, high mental quality and introverted character, and this part of the patients show obvious symptoms and have a longer course of the disease. For patients with psychological disorders of infertility, the main thing is to rely on psychotherapy. Psychotherapy is multifaceted and relies on the doctor as well as the family and oneself. For the psychological disorder symptoms are obvious, should be timely to the regular hospital to find the official doctor consultation, clear infertility causes, distinguish between relative infertility or absolute infertility, in the clear disease on the basis of the appropriate treatment measures, as soon as possible to relieve the pain of infertility. It must be emphasized that the patient must improve the ideological awareness, understanding of medical knowledge, enhance the ability of self-control of the disease and the ability to adapt to infertility, do not have to be at a loss for a moment of infertility, not because of a certain disease chagrin. Negative psychology can only increase the extent of the disease, and positive psychology is beneficial to drive out the disease. A large number of clinical data proved that excessive mental tension, psychological disorders, often lead to endocrine dysfunction, ovulation disorders, the formation of the more you want to get pregnant, the more difficult to get pregnant situation. This reasoning should be understood by the patients themselves and their family members. In the process of treatment, the role of family members, especially the husband, should not be ignored. For infertility patients, we should respect them, care for them, considerate them, usually should not discuss about infertility how to how such topics, family members should not intentionally or unintentionally blame, rebuke, sarcasm, and the need is to enlightenment, encouragement, help, which is not only conducive to the patient’s recovery, but also conducive to family harmony, social stability. At the same time, patients should also improve their own “immunity”, to maintain psychological health, reduce doubts, worries, self-blame, low self-esteem, do not complain, do not avoid medical treatment, not a bull’s-eye. To do this, the first is to improve the understanding, and the understanding of the need to have basic medical knowledge. Clinical observation suggests that cadres and scientific and technological personnel with higher cultural level, rich medical knowledge and stronger self-regulation ability have much lower incidence of psychological disorders after infertility than patients with low cultural level, poor medical knowledge and poor self-regulation ability. Reducing or mitigating psychological disorders in infertility patients will not only increase the rate of natural conception, but also improve the quality of life of the patients, which is indeed an issue that deserves great attention from society as a whole.