If once unfortunate to find out the glioma, do not be nervous first, according to their own condition individualized comprehensive analysis, for their own choice of a correct treatment plan is especially major. We combined with the 2015 CNS glioma diagnosis and treatment guidelines to give you an explanation: the treatment of glioma is mainly surgical treatment, but due to the infiltrative growth of the tumor, there is no obvious boundary between the brain tissue, except for the early tumor is small and located in the non-functional area, it is difficult to make a total resection, generally advocate comprehensive treatment, that is, postoperative treatment with radiation therapy, chemotherapy, etc., which can delay recurrence and prolong the survival period, and should strive for early diagnosis and timely treatment to improve the quality of life of the patient, and to improve the quality of life of the patient. In general, comprehensive treatment is advocated, i.e., postoperative radiotherapy and chemotherapy, which can delay recurrence and prolong the survival period, and should strive for early diagnosis and timely treatment to improve the treatment effect. Late stage is not only difficult and dangerous for surgery, but also often leaves neurological deficits. Especially high-grade glioma often recurs in a short period of time. Surgery: The principle is to remove the tumor to the largest extent under the premise of preserving nerve function. Surgical resection is preferred for relatively superficial and large gliomas. Surgery is carried out completely under microscope, and microscopic neurosurgical techniques are adopted to strive for anatomical resection along the edge of the tumor, so as to maximize tumor resection with the minimum degree of tissue and neurological damage, and to resect the tumor under the operation of conventional neuronavigation, functional neuronavigation, intraoperative neuronavigation with neurophysiological detection and fluorescence technology, intraoperative MRI real-time imaging neuronavigation, intraoperative ultrasound and other operations. Functional area glioma surgery (which involves the patient’s limb movement and speech function) is a major difficulty in neurosurgery at home and abroad. We use the most advanced intraoperative wake-up technology, i.e., during the process of removing the patient’s tumor, the patient retains the motor and speech functions, and during the process of removing the tumor, the patient is asked to move the limbs and talk with the medical staff, so that the scope of surgical resection does not exceed the functional area in real time. This technique is a great challenge for anesthesiologists and neurosurgeons. For low-grade gliomas with epileptic symptoms only, which can be well controlled by drugs and located in the main functional area or when the tumor is small, due to the possibility of disability caused by the surgery, it can be “watched and waited” under the stable state of the image. For low-grade gliomas in non-functional areas or adjacent functional areas, brain functional localization techniques can be used to identify cortical and subcortical structures related to key brain functions, especially language, so that the surgery can be carried out in accordance with the functional boundaries of the resection, in order to achieve the maximum safe resection of low-grade gliomas, including total or even ultra-total resection. II. Radiation therapy: Radiation sources used for extracorporeal irradiation include high-voltage x-ray therapy machines, 60Co therapy machines, and electron gas pedals. The latter two belong to high-energy rays, strong penetration, low skin dose, small bone absorption, less side scattering. Gas pedals, on the other hand, concentrate the dose at the expected depth, beyond which the dose drops sharply, and can protect the normal brain tissue behind the lesion. Radiation therapy is preferred to be given as early as possible after recovery of general condition after surgery. The irradiation dose is usually 5000-6000 cGy given for neurogliomas and is completed within 5-6 weeks. The sensitivity of various types of gliomas to radiation therapy varies. Poorly differentiated tumors are generally considered to be more highly differentiated than well-differentiated ones. Glioblastoma multiforme is only moderately sensitive, and astrocytomas, oligodendrogliomas, and pinealocytomas are somewhat worse. Ventricular meningioma, because of easy dissemination with cerebrospinal fluid, should include total spinal canal irradiation. Third, chemotherapy: chemotherapeutic drugs with high lipid solubility that can pass the blood-brain barrier are suitable for cerebral gliomas. In astrocytoma grade III~IV, the blood-brain barrier is destroyed due to edema, so that the water-soluble macromolecular drugs can pass, so some people think that the selection of drugs can be expanded to many water-soluble molecules. However, in fact, the destruction of blood-brain barrier is not serious in the dense proliferating cells around the tumor. Therefore, the choice of drugs should still be mainly fat-soluble, and the main drug at present is temozolomide (TMZ), and for mesenchymal oligodendroglioma (AO), the PCV program can be chosen. Surgical cavity can be implanted with BCNU palliative chemotherapy. Symptomatic treatment: treatment of cerebral edema and increased intracranial pressure; treatment of epilepsy; prevention of deep vein thrombosis (VTE); symptomatic treatment of psychiatric symptoms. V. Rehabilitation therapy: physical therapy; occupational therapy; speech and swallowing therapy; cognitive and behavioral therapy; recreational therapy; psychological rehabilitation; rehabilitation engineering; medication; traditional Chinese medicine. Multidisciplinary collaborative treatment (MDT): Composed of relevant doctors and medical related professionals, who should be able to formulate precise and effective individualized treatment plans for tumor patients.